Ōoku: The Inner Chambers

🇯🇵大奥 · Oooku

MangaShoujoFinished🇯🇵 First published in 2004DramaRomanceSlice of Life

Fumi Yoshinaga story, art · Eric Montesinos art

In Edo period Japan, a strange new disease called the Redface Pox has begun to prey on the country's men. Within eighty years of the first outbreak, the male population has fallen by seventy-five percent. Women have taken on all the roles traditionally granted to men, even that of the shogun. The men, precious providers of life, are carefully protected.

Synopsis via AniList